In 2009, we moved to Santa Fe, a land of abundant dirt and clean air close to the sun. It’s a slice of heaven, but living on the New Mexican high desert takes its toll on skin. Ours began to show signs of age along with a little rosacea, and even the most expensive creams and serums can irritate it.
Reading up on the CBD research happening around the world, we were excited to learn about the human endocannabinoid system and its receptors, and how hemp has grown alongside human civilization for thousands of years—one of our oldest plant relationships which feeds, clothes, and shelters us.
The human endocannabinoid system
We are biologically primed to use cannabinoids. The relationship between humans and cannabis has been developing for more than 8,000 years, and it is a plant that can feed, clothe, and shelter us.
The human body actually has an endocannabinoid system, through which it produces its own cannabinoids, representing a complex system of repair. Most, if not all, skin functions are controlled to a certain extent by the skin’s endocannabinoid system. We also have CB1 and CB2 receptors which synthesize the topical application of CBD.
Our endocannabinoid system controls skin inflammation—so if an inflammatory or irritation challenge assaults the skin, the endocannabinoid system fights against it.
The “entourage effect”
While CBD has emerged as the star player in the cannabis spectrum, evidence suggests that it is boosted by combining it with other active molecules from the cannabis plant, including other phytocannabinoids, terpenes and flavonoids, which can also have beneficial effects.
This phenomenon, known as the “entourage effect,” was first recognized by Raphael Mechoulam, PhD, the Israeli organic chemist who first identified the presence of CBD in cannabis in the 1960s.